Bacteria can synthesize and secrete cellulosic polymers using membrane-associated multiprotein complexes consisting of cellulose synthases and accessory subunits. Here, Anso et al. use cryogenic electron microscopy to shed light on the mechanisms underlying accessory subunit recruitment and function within the Bcs macrocomplex for phosphoethanolamine-modified cellulose secretion in E. coli.
- Itxaso Anso
- Samira Zouhir
- Petya Violinova Krasteva