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Showing 1–4 of 4 results
Advanced filters: Author: Samy Gobaa Clear advanced filters

  • Contact spotting with standard microarray printing tools can be used to generate high-density arrays of living mammalian cells, permitting the arraying of cell libraries without complex fluid manipulation.

    • Kristina Woodruff
    • Luis M Fidalgo
    • Sebastian J Maerkl
    Research
    Nature Methods
    Volume: 10, P: 550-552

  • Haematopoietic stem cell (HSC) self-renewal is not sufficiently understood to recapitulate in vitro. Here, the authors generate gene signature and cell cycle hallmarks of single murine HSCs, and use identified endothelial receptors Esam and JamC as substrates to enhance HSC growth in engineered niches.

    • Aline Roch
    • Sonja Giger
    • Matthias P. Lutolf
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • Soft hydrogel microwell arrays with controllably variable stiffness are spotted with proteins of interest, individually or in combination. The system permits in vitro study of the biophysical and biochemical aspects of the stem-cell niche.

    • Samy Gobaa
    • Sylke Hoehnel
    • Matthias P Lutolf
    Research
    Nature Methods
    Volume: 8, P: 949-955