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Nature Immunology (2)
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Conserved stromal–immune cell circuits secure B cell homeostasis and function

Pikor et al. show that a set of conserved, bidirectional cues exchanged between fibroblastic reticular cells and immune cells sustain B cell niches, which control humoral immune responses across mouse and human lymphoid organs.

Mechthild Lütge
Angelina De Martin
Natalia B. Pikor
ResearchOpen Access18 May 2023
Nature Immunology

Volume: 24, P: 1149-1160
PI16⁺ reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial niches

De Martin, Ludewig and colleagues define the topology and molecular identity of human tonsillar stromal cells and show that PI16-expressing fibroblastic reticular cells shape subepithelial niches for efficient T cell activation and differentiation.

Angelina De Martin
Yves Stanossek
Burkhard Ludewig
ResearchOpen Access18 May 2023
Nature Immunology

Volume: 24, P: 1138-1148
Maximum Standardized Uptake Value (SUV_max) of Primary Tumor Predicts Occult Neck Metastasis in Oral Cancer

Grégoire B. Morand
Domenic G. Vital
Martin W. Huellner
ResearchOpen Access07 Aug 2018
Scientific Reports

Volume: 8, P: 1-7