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Showing 1–3 of 3 results
Advanced filters: Author: Sandy Bauherr Clear advanced filters

  • Innate lymphoid cells (ILCs) are important regulators of biological processes. Here the authors combine multiplexed imaging and computational pipelines to reveal tonsillar IRF4+ ILC3s, and to identify conserved stromal landmarks for ILC localization, thereby providing a platform for future ILC studies.

    • Anna Pascual-Reguant
    • Ralf Köhler
    • Anja E. Hauser
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Our understanding on the humoral immunity induced by SARS-CoV-2 is still lacking. Here the authors analyze B cell responses at the single cell level to find that, in severe COVID-19 patients, plasmablasts shift from IFN to TGFβ instruction to produce IgA antibodies that are not specific to dominant SARS-CoV-2 antigens.

    • Marta Ferreira-Gomes
    • Andrey Kruglov
    • Mir-Farzin Mashreghi
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • Infection with SARS-CoV-2 has been linked with substantive inflammation, lung pathology and development of COVID-19. Here the authors spatially associate CCL18 and CCL21 in distinct tissue niches with lung pathology of severe COVID-19.

    • Ronja Mothes
    • Anna Pascual-Reguant
    • Anja E. Hauser
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16