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Showing 1–3 of 3 results
Advanced filters: Author: Sanjit S. Batra Clear advanced filters

  • It is challenging to analyse chromosomal rearrangements in heterogeneous solid cancers. Here the authors present HiDENSEC, a method to jointly infer absolute copy number, ploidy, tumor purity and large-scale rearrangements from Hi-C data. The increased statistical power afforded by joint inference enables novel insights into cancer genome evolution.

    • Dan Daniel Erdmann-Pham
    • Sanjit Singh Batra
    • Dirk Hockemeyer
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Frogs are an ancient and ecologically diverse group of amphibians that include important model systems. This paper reports genome sequences of multiple frog species, revealing remarkable stability of frog chromosomes and centromeres, along with highly recombinogenic extended subtelomeres.

    • Jessen V. Bredeson
    • Austin B. Mudd
    • Daniel S. Rokhsar
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • An improved, fully re-annotated Aedes aegypti genome assembly (AaegL5) provides insights into the sex-determining M locus, chemosensory systems that help mosquitoes to hunt humans and loci involved in insecticide resistance and will help to generate intervention strategies to fight this deadly disease vector.

    • Benjamin J. Matthews
    • Olga Dudchenko
    • Leslie B. Vosshall
    ResearchOpen Access
    Nature
    Volume: 563, P: 501-507