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Showing 1–13 of 13 results
Advanced filters: Author: Sapun H. Parekh Clear advanced filters

  • An atomic force microscope with a side-view fluorescent imaging path facilitates the direct correlation of mechanical force measurements with observations of changes in cell shape and cytoskeleton rearrangements resulting from the applied forces or during active generation of forces by the cell. The combined instrument could help lead to insights in understanding cell mechanics, contractility and cell-cell adhesion.

    • Ovijit Chaudhuri
    • Sapun H Parekh
    • Daniel A Fletcher
    Research
    Nature Methods
    Volume: 6, P: 383-387

  • Adding short, complementary oligonucleotides to single-stranded DNA condensates creates a concentrated, linearly propagating, sharp diffusion front that contradicts the fuzzy concentration gradients and nonlinear kinetics typical of Fickian diffusion.

    • Weixiang Chen
    • Brigitta Dúzs
    • Andreas Walther
    ResearchOpen Access
    Nature Nanotechnology
    Volume: 20, P: 1062-1070

  • NMR and Raman spectroscopies pinpoint the role of the protein droplet surface and RNA in the liquid droplet maturation mechanism of the FUS protein. A crust-like β-sheet structure is formed on the surface of FUS droplets during aging.

    • Leonidas Emmanouilidis
    • Ettore Bartalucci
    • Frédéric H.-T. Allain
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 20, P: 1044-1052

  • Protein solutions can undergo liquid–liquid phase separation, by condensing into a dense phase that often resembles liquid droplets, which coexist with a dilute phase. Now it is shown that hydrophobic interactions, specifically at interfaces, can trigger a liquid–solid phase separation of a protein solution.

    • Daria Maltseva
    • Sayantan Chatterjee
    • Mischa Bonn
    ResearchOpen Access
    Nature Chemistry
    Volume: 15, P: 1146-1154

  • Methylammonium lead iodide perovskite, a promising material for efficient photovoltaics, shows a unique temperature dependence of its optical properties. Kim et al. quantify the coupling between the optical gap and a lattice phonon at 1 THz, which favorably contributes to the thermal variation of the gap.

    • Heejae Kim
    • Johannes Hunger
    • Mischa Bonn
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9

  • Inspired by the post-translational modifications of polypeptides widespread in biological systems, the one-pot synthesis of biohybrid materials was engineered within Escherichia coli using a recombinant expression and post-translational lipidation. The fatty-acid-modified elastin-like polypeptides (FAMEs) prepared, which comprise peptide-amphiphile segments prone to self-assembly fused to a thermally responsive elastin-like polypeptide, exhibit temperature-triggered hierarchical assembly.

    • Davoud Mozhdehi
    • Kelli M. Luginbuhl
    • Ashutosh Chilkoti
    Research
    Nature Chemistry
    Volume: 10, P: 496-505

  • This Perspective reviews the complementary developments in synthetic biology and biomaterials and discusses how convergence of these two fields creates a promising design strategy for the fabrication of tailored living materials for medicine and biotechnology.

    • Allen P. Liu
    • Eric A. Appel
    • Ovijit Chaudhuri
    Reviews
    Nature Materials
    Volume: 21, P: 390-397