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Showing 1–7 of 7 results

Advanced filters: Author: Sara Ballabio Clear advanced filters

The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans

The mammalian protein TFEB is a key regulator of autophagy, a cellular process implicated in organismal ageing. Here, Lapierre et al. show that the TFEB orthologue HLH-30 is required for lifespan extension in six different long-lived Caenorhabditis elegansstrains.

Louis R. Lapierre
C. Daniel De Magalhaes Filho
Malene Hansen
Research08 Aug 2013
Nature Communications

Volume: 4, P: 1-8
Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health

Daly, Danson and colleagues employ a multi-omic approach in neuroglioma cells to characterise endolysosomal dysfunction caused by perturbation of the evolutionarily conserved Retromer complex, highlighting Retromer’s neuroprotective function.

James L. Daly
Chris M. Danson
Peter J. Cullen
ResearchOpen Access29 May 2023
Nature Communications

Volume: 14, P: 1-19
The DNA sequence of the human X chromosome

Mark T. Ross
Darren V. Grafham
David R. Bentley
Research17 Mar 2005
Nature

Volume: 434, P: 325-337
Investigation of dynamic regulation of TFEB nuclear shuttling by microfluidics and quantitative modelling

Mathematical modelling and real-time microfluidics-based measurements of nuclear shuttling dynamics of the transcription factor EB (TFEB) demonstrate its biphasic nature in response to nutrient deprivation caused by (de)phosphorylation events.

Iacopo Ruolo
Sara Napolitano
Diego di Bernardo
ResearchOpen Access15 Mar 2025
Communications Biology

Volume: 8, P: 1-14
Evidence for interaction between human PRUNE and nm23-H1 NDPKinase

Alexandre Reymond
Sara Volorio
Massimo Zollo
Research08 Dec 1999
Oncogene

Volume: 18, P: 7244-7252
Correction: Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

Ezia Bello
Silvia Brich
Roberta Frapolli
Amendments and Corrections11 Feb 2020
British Journal of Cancer

Volume: 122, P: 1120
Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

Ezia Bello
Silvia Brich
Roberta Frapolli
ResearchOpen Access14 Aug 2019
British Journal of Cancer

Volume: 121, P: 464-473