AQP3 facilitates the transport of hydrogen peroxide. Here the authors report cryo-EM structures of AQP3 under different pH and in the presence of hydrogen peroxide. Along with molecular dynamics simulations, the study reveals how AQP3 maintains redox balance in endocrine pancreas.
- Peng Huang
- Raminta Venskutonytė
- Karin Lindkvist-Petersson
