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Showing 1–4 of 4 results

Advanced filters: Author: Sara I. Liin Clear advanced filters

Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism

Here, the authors demonstrate how Mrs2, critical for import of Mg²⁺ into the mitochondria, transitions from open and closed five-fold symmetric states to control the influx of Mg²⁺ using an auto-ligand-gating regulation mechanism.

Ping Li
Shiyan Liu
Pontus Gourdon
ResearchOpen Access28 Nov 2024
Nature Structural & Molecular Biology

Volume: 32, P: 491-501
KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

The mechanism by which KCNEβ subunits slow the kinetics of KCNQ1 channels is controversial. Here, Barro-Soria et al.show that mutually independent voltage sensor movements underlie the initial activation delay, and a subsequent slower conformational change opens the channel.

Rene Barro-Soria
Santiago Rebolledo
H. Peter Larsson
Research28 Apr 2014
Nature Communications

Volume: 5, P: 1-12
Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation

Luca Conti
Jakob Renhorn
Fredrik Elinder
ResearchOpen Access09 Jun 2016
Scientific Reports

Volume: 6, P: 1-13
Electronic polymers in lipid membranes

Patrik K. Johansson
David Jullesson
Olle Inganäs
ResearchOpen Access10 Jun 2015
Scientific Reports

Volume: 5, P: 1-11