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Showing 51–88 of 88 results

Advanced filters: Author: Sarah Atkinson Clear advanced filters

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

STAAR is a powerful rare variant association test that incorporates variant functional categories and complementary functional annotations using a dynamic weighting scheme based on annotation principal components. STAAR accounts for population structure and relatedness and is scalable for analyzing large whole-genome sequencing studies.

Xihao Li
Zilin Li
Xihong Lin
Research24 Aug 2020
Nature Genetics

Volume: 52, P: 969-983
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Brian J. Willett
Joe Grove
Emma C. Thomson
Amendments and CorrectionsOpen Access16 Sept 2022
Nature Microbiology

Volume: 7, P: 1709
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes

Christopher E Lowe
Jason D Cooper
John A Todd
Research05 Aug 2007
Nature Genetics

Volume: 39, P: 1074-1082
Interdependency of tropical marine ecosystems in response to climate change

Linkages between neighbouring ecosystems are rarely considered when seeking to predict ecological responses to climate change. However, the finding that the impact of climate change on seagrass beds is mediated by the response of neighbouring coral reef habitats highlights the need for a broader-scale view of climate change impacts on ecosystems.

Megan I. Saunders
Javier X. Leon
Peter J. Mumby
Research22 Jun 2014
Nature Climate Change

Volume: 4, P: 724-729
The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

HuBMAP supports technology development, data acquisition, and spatial analyses to generate comprehensive molecular and cellular three-dimensional tissue maps.

Michael P. Snyder
Shin Lin
James Anderson
ReviewsOpen Access09 Oct 2019
Nature

Volume: 574, P: 187-192
Doing more with movement: constituting healthy publics in movement volunteering programmes

Emily Tupper
Sarah Atkinson
Tessa M. Pollard
ResearchOpen Access13 May 2020
Palgrave Communications

Volume: 6, P: 1-11
Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Genome-wide association meta-analyses among 1.4 million individuals identify 318 new risk loci for type 2 diabetes and provide insight into the contribution of these risk variants to diabetes-related vascular outcomes.

Marijana Vujkovic
Jacob M. Keaton
Danish Saleheen
Research15 Jun 2020
Nature Genetics

Volume: 52, P: 680-691
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17
Reversal of Phencyclidine-Induced Dopaminergic Dysregulation by N-Methyl-D-Aspartate Receptor/Glycine-site Agonists

Daniel C Javitt
Andrea Balla
Henry Sershen
Research15 Oct 2003
Neuropsychopharmacology

Volume: 29, P: 300-307
CITRINO: phase 1 dose escalation study of anti-LAG-3 antibody encelimab alone or in combination with anti-PD-1 dostarlimab in patients with advanced/metastatic solid tumours

J. Randolph Hecht
Jean-Marie Michot
Susanna Ulahannan
ResearchOpen Access27 Feb 2025
BJC Reports

Volume: 3, P: 1-11
Malaria is a cause of iron deficiency in African children

A genetic link suggests that interventions that halve the risk of malaria episodes could reduce the prevalence of iron deficiency in African children by nearly 50%.

John Muthii Muriuki
Alexander J. Mentzer
Sarah H. Atkinson
Research22 Feb 2021
Nature Medicine

Volume: 27, P: 653-658
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Maja Kopczynska
Harry Unwin
Judith E. Hall
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
Local exposure misclassification in national models: relationships with urban infrastructure and demographics

Sarah E. Chambliss
Mark Joseph Campmier
Corwin M. Zigler
ResearchOpen Access22 Dec 2023
Journal of Exposure Science & Environmental Epidemiology

Volume: 34, P: 761-769
Aquatic deoxygenation as a planetary boundary and key regulator of Earth system stability

Deoxygenation is rapidly occurring in marine and freshwater habitats worldwide. This Perspective proposes that deoxygenation should be considered as a planetary boundary, discusses how deoxygenation affects Earth systems and describes interactions with several other described planetary boundaries.

Kevin C. Rose
Erica M. Ferrer
Denise Breitburg
Reviews15 Jul 2024
Nature Ecology & Evolution

Volume: 8, P: 1400-1406
Murine Model for Cystic Fibrosis Bone Disease Demonstrates Osteopenia and Sex-Related Differences in Bone Formation

Troy D Pashuck
Sarah E Franz
Michael S Stalvey
Research01 Mar 2009
Pediatric Research

Volume: 65, P: 311-316
Diet-driven mercury contamination is associated with polar bear gut microbiota

Sophie E. Watson
Melissa A. McKinney
Sarah E. Perkins
ResearchOpen Access03 Dec 2021
Scientific Reports

Volume: 11, P: 1-11
Recommendations to address respondent burden associated with patient-reported outcome assessment

Patient-reported outcomes are invaluable tools, but may impose a burden on patients; this consensus statement provides a set of 19 recommendations to reduce respondent burden.

Olalekan Lee Aiyegbusi
Samantha Cruz Rivera
Melanie J. Calvert
Reviews29 Feb 2024
Nature Medicine

Volume: 30, P: 650-659
Waterborne pathogen monitoring in Jaipur, India reveals potential microbial risks of urban groundwater supply

Aaron Bivins
Sarah Lowry
Joe Brown
ResearchOpen Access23 Jul 2020
npj Clean Water

Volume: 3, P: 1-10
Global change-driven use of onshore habitat impacts polar bear faecal microbiota

Sophie E. Watson
Heidi C. Hauffe
Sarah E. Perkins
Research05 Aug 2019
The ISME Journal

Volume: 13, P: 2916-2926
Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V

Sarah C. Atkinson
Michelle D. Audsley
Natalie A. Borg
ResearchOpen Access10 Jan 2018
Scientific Reports

Volume: 8, P: 1-17
A human neurodevelopmental model for Williams syndrome

A human neurodevelopmental model fills the current knowledge gap in the cellular biology of Williams syndrome and could lead to further insights into the molecular mechanism underlying the disorder and the human social brain.

Thanathom Chailangkarn
Cleber A. Trujillo
Alysson R. Muotri
Research10 Aug 2016
Nature

Volume: 536, P: 338-343
Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen
Laurent C. Francioli
Konrad J. Karczewski
Amendments and Corrections15 Jan 2024
Nature

Volume: 626, P: E1
Assessing and addressing the global state of food production data scarcity

Accurate and timely food production data are needed to promote food security and sustainability, but data scarcity exists across national and international levels. This Review examines data availability and reliability for crops, livestock and aquatic food production and recommends solutions to address data scarcity.

Endalkachew Abebe Kebede
Hanan Abou Ali
Kyle Frankel Davis
Reviews20 Feb 2024
Nature Reviews Earth & Environment

Volume: 5, P: 295-311
Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy

Zabrina L. Brumme
Francis Mwimanzi
Mark A. Brockman
ResearchOpen Access28 Feb 2022
npj Vaccines

Volume: 7, P: 1-12
C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis

Jennifer K. Mulligan
Kunal Patel
Carl Atkinson
Research15 Jun 2018
Mucosal Immunology

Volume: 11, P: 1375-1385
Long non-coding RNA PARTICLE bridges histone and DNA methylation

Valerie Bríd O’Leary
Sarah Hain
Michael John Atkinson
ResearchOpen Access11 May 2017
Scientific Reports

Volume: 7, P: 1-12
PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome

Valerie Bríd O’Leary
Jan Smida
Michael John Atkinson
ResearchOpen Access02 Aug 2017
Scientific Reports

Volume: 7, P: 1-13
Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study

Shanice Christie
Sébastien Robiou-du-Pont
David Meyre
ResearchOpen Access06 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Antimicrobial Peptide Potency is Facilitated by Greater Conformational Flexibility when Binding to Gram-negative Bacterial Inner Membranes

Sarah-Beth T. A. Amos
Louic S. Vermeer
A. James Mason
ResearchOpen Access22 Nov 2016
Scientific Reports

Volume: 6, P: 1-13
The relationship between interoception and agency and its modulation by heartbeats: an exploratory study

Akihiro Koreki
Diana Goeta
Mahinda Yogarajah
ResearchOpen Access10 Aug 2022
Scientific Reports

Volume: 12, P: 1-10
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Jonathan E. Millar
Lucile Neyton
Peter Young
ResearchOpen Access27 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
Public attitudes toward COVID-19 vaccination: The role of vaccine attributes, incentives, and misinformation

Sarah Kreps
Nabarun Dasgupta
Douglas L. Kriner
ResearchOpen Access14 May 2021
npj Vaccines

Volume: 6, P: 1-7
Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase

Ellie Edlmann
Eric P. Thelin
Nikolaos Tzerakis
ResearchOpen Access10 Apr 2019
Scientific Reports

Volume: 9, P: 1-13
A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses

Niila V. V. Saarinen
Jutta E. Laiho
Olli H. Laitinen
ResearchOpen Access08 Jan 2018
Scientific Reports

Volume: 8, P: 1-13
Implementation of a fully remote randomized clinical trial with cardiac monitoring

Mayfield et al. describe the implementation and feasibility of an exclusively remote randomized clinical trial of hydroxychloroquine and azithromycin for the treatment of COVID-19. The trial included monitoring of cardiovascular safety which was successfully done using digital technologies.

Jacob J. Mayfield
Neal A. Chatterjee
Arun R. Sridhar
ResearchOpen Access20 Dec 2021
Communications Medicine

Volume: 1, P: 1-10
Enhanced IgE allergic response to Aspergillus fumigatus in CFTR−/− mice

Christian Müller
Sofia A Braag
Terence R Flotte
Research12 Dec 2005
Laboratory Investigation

Volume: 86, P: 130-140
Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study

Gerard Sanacora
Michael R Johnson
Sanjeev Pathak
ResearchOpen Access29 Sept 2016
Neuropsychopharmacology

Volume: 42, P: 844-853

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