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Showing 1–4 of 4 results
Advanced filters: Author: Sarah Batson Clear advanced filters

  • An extracorporeal cross-circulation approach enables, in a swine model, 36 hours of normothermic perfusion in healthy lungs, the recovery of injured lungs, and extended therapeutic interventions in all lungs.

    • John D. O’Neill
    • Brandon A. Guenthart
    • Gordana Vunjak-Novakovic
    Research
    Nature Biomedical Engineering
    Volume: 1, P: 1-15

  • The antibiotic D-cycloserine (DCS) targets the peptidoglycan biosynthesis enzyme D-Ala-D-Ala ligase (Ddl). Here the authors reveal the DCS inhibitory mechanism by determining the structure of E. coli DdlB with a phosphorylated DCS molecule in the active site that formed in crystallo and mimics the D-alanyl phosphate intermediate.

    • Sarah Batson
    • Cesira de Chiara
    • David I. Roper
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7

  • In this study, the authors provide a global overview of SARS-CoV-2 genome sequencing, and estimate the proportion of cases sequenced and time to genome upload. They identify disparities and highlight the need to strengthen surveillance in lower and middle income countries.

    • Anderson F. Brito
    • Elizaveta Semenova
    • Nuno R. Faria
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Epidermal growth factor receptors have been shown to oligomerise upon binding to their cognate ligands. Here, the authors use biochemical, biophysical and cell biology techniques to analyse the structures of these oligomers, and argue that these formations are required for signalling.

    • Sarah R. Needham
    • Selene K. Roberts
    • Marisa L. Martin-Fernandez
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-14