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Showing 1–4 of 4 results
Advanced filters: Author: Sarah Guiziou Clear advanced filters

  • Genetic logic devices allow the host cell to incorporate multiple inputs to determine output behaviour. Here the authors provide a framework for engineering reliable recombinase-based devices and demonstrate 4-input logic in a multicellular system.

    • Sarah Guiziou
    • Pauline Mayonove
    • Jerome Bonnet
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-7

  • Understanding gene expression patterns that underlie developmental programs can inform engineering efforts for new or optimized forms. Here, the authors engineer a four-state history-dependent integrase-based recorder of gene expression in Arabidopsis and show its application in two developmental programs.

    • Cassandra J. Maranas
    • Wesley George
    • Sarah Guiziou
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • Synthetic circuits that can record in vivo signaling networks is critical in elucidating developmental process. Here, the authors describe the engineering and application of synthetic in vivo recorders with different promoters that can drive spatiotemporally-specific integrase switching during lateral root initiation.

    • Sarah Guiziou
    • Cassandra J. Maranas
    • Jennifer L. Nemhauser
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13