RNA-cleaving DNAzymes exhibit potential as biosensors and in vivo knockdown agents, however, the structures of DNAzymes remain underexplored. Here, the authors report the 2.7 Å X-Ray crystal structure of a 10-23 DNAzyme–substrate complex in a homodimer conformation.
- Evan R. Cramer
- Sarah A. Starcovic
- Aaron R. Robart
