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Showing 1–3 of 3 results
Advanced filters: Author: Sarah Waldvogel Clear advanced filters

  • Isolating and studying haematopoietic stem cells in young and aged mice demonstrates evolutionary processes related to blood production and provides a framework for interpreting future work using laboratory mice to study stem cell ageing.

    • Chiraag D. Kapadia
    • Nicholas Williams
    • Jyoti Nangalia
    ResearchOpen Access
    Nature
    Volume: 641, P: 681-689

  • Genetic variants acquired early during embryogenesis can affect numerous tissues. The authors review the phenomenon of embryonic mosaicism, with a focus on small variants, and discuss mechanisms of cell competition that allow mosaic clones to expand, as well as the functional consequences of mosaicism for embryo viability and the health of the organism.

    • Sarah M. Waldvogel
    • Jennifer E. Posey
    • Margaret A. Goodell
    Reviews
    Nature Reviews Genetics
    Volume: 25, P: 698-714