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Showing 1–3 of 3 results
Advanced filters: Author: Sarah-Jane Richards Clear advanced filters
  • Distinguishing between different proteins that each bind to the same type of glycan is challenging. Here, the authors demonstrate that an enzymatically synthesised library of Lewisx ‘glycofluoroforms’ that feature site-specific fluorination can discriminate closely related proteins.

    • Kristian Hollingsworth
    • Antonio Di Maio
    • Bruno Linclau
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14
  • A stiff hydrogel gel is presented that encapsulates and stabilizes proteins without additives or excipients and uses mechanical strain to release them, offering low-cost and versatile delivery of therapies.

    • Simona Bianco
    • Muhammad Hasan
    • Dave J. Adams
    ResearchOpen Access
    Nature
    Volume: 631, P: 544-548
  • Previous work has identified several genes where mutations lead to breast cancer, but other genetic and environmental factors must still be accounted for. A large study of genetic association with breast cancer points to four novel genes and many more genetic markers that should be pursued for their link to cancer susceptibility.

    • Douglas F. Easton
    • Karen A. Pooley
    • Bruce A. J. Ponder
    Research
    Nature
    Volume: 447, P: 1087-1093