Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Sasha Ebrahimi Clear advanced filters

  • Ebrahimi and Samanta review the key advances in the chemical and structural modification of proteins that have enabled their rise as indispensable tools in medicine and outline emerging protein engineering strategies that can potentially unlock structures with improved therapeutic properties.

    • Sasha B. Ebrahimi
    • Devleena Samanta
    ReviewsOpen Access
    Nature Communications
    Volume: 14, P: 1-11

  • While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice.

    • Gabriel Oh
    • Sasha Ebrahimi
    • Art Petronis
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11

  • Oligonucleotide therapeutics have emerged as a promising alternative to traditional small-molecule and protein-based drugs. This Perspective discusses how chemical engineering can broaden oligonucleotide applications to extrahepatic diseases and enable larger-scale production, ultimately allowing treatment of more prevalent conditions than is currently possible.

    • Sasha B. Ebrahimi
    • Himanshu Bhattacharjee
    • Devleena Samanta
    Reviews
    Nature Chemical Engineering
    Volume: 1, P: 741-750

  • Damaged DNA is often targeted to nuclear pore complexes for repair. Here, the authors show that kinesin-14 mediates this process ensuring error-prone repair, while perinuclear telomere attachment licenses damaged telomeric loci for this repair and kinesin-14 blocks senescence in the absence of telomerase.

    • Daniel K.C. Chung
    • Janet N.Y. Chan
    • Karim Mekhail
    Research
    Nature Communications
    Volume: 6, P: 1-13

  • Mirkin and colleagues outline the synthesis of protein spherical nucleic acids (ProSNAs), which constitute a versatile plug-and-play platform that uses protein functionalization with a dense nucleic acid corona to enable intracellular delivery both in vitro and in vivo.

    • Sasha B. Ebrahimi
    • Devleena Samanta
    • Chad A. Mirkin
    Protocols
    Nature Protocols
    Volume: 17, P: 327-357