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  • Ada Gjyrezi et al. show that ddPCR can be used to accurately measure androgen receptor variant (AR-V) expression levels in single circulating tumor cells (CTCs) from prostate cancer patients. They show that current methods for isolating CTCs tend to underestimate the prevalence of AR-V and that a specific variant, AR-v567es, could be potentially used as a biomarker for an aggressive subtype of prostate cancer.

    • Ada Gjyrezi
    • Giuseppe Galletti
    • Paraskevi Giannakakou
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-9