Nature Search

Five rules for scientifically credible nature markets

This Perspective synthesizes insights from the past use of nature markets to identify design factors that are necessary if such markets are to achieve their environmental aims—although qualitative scoring of existing markets against these rules identifies pervasive gaps.

Sophus O.S.E. zu Ermgassen
Tom Swinfield
Megan C. Evans
Reviews12 Jan 2026
Nature Ecology & Evolution

P: 1-12
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease

Here, the authors reveal using single-cell RNA sequencing that Parkinson’s disease (PD) patient-derived neuronal cells show altered primary cilia morphology and signaling suggesting cilia dysfunction may underlie PD pathogenesis.

Sebastian Schmidt
Malte D. Luecken
Wolfgang Wurst
ResearchOpen Access16 Aug 2022
Nature Communications

Volume: 13, P: 1-25
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma

Branched organoids embedded in collagen gels can recapitulate the phenotypic landscape and pronounced molecular and morphological heterogeneity of pancreatic ductal adenocarcinoma.

Aristeidis Papargyriou
Mulham Najajreh
Maximilian Reichert
ResearchOpen Access10 Dec 2024
Nature Biomedical Engineering

Volume: 9, P: 836-864
Quantitative characterization of cell niches in spatially resolved omics data

NicheCompass is a graph variational autoencoder approach for identifying cellular niches defined by cell–cell communication and other interactions, applicable to a broad variety of spatial multi-omic data.

Sebastian Birk
Irene Bonafonte-Pardàs
Mohammad Lotfollahi
ResearchOpen Access18 Mar 2025
Nature Genetics

Volume: 57, P: 897-909
Comparing multi-texture fibrosis analysis versus binary opacity-based abnormality detection for quantitative assessment of idiopathic pulmonary fibrosis

Sebastian Nowak
Dominik Creuzberg
Daniel Kütting
ResearchOpen Access09 Jan 2025
Scientific Reports

Volume: 15, P: 1-9
A reversible state of hypometabolism in a human cellular model of sporadic Parkinson’s disease

Mitochondrial dysfunction is a contributing factor in Parkinson’s disease. Here the authors carry out a multilayered omics analysis of Parkinson’s disease patient-derived neuronal cells, which reveals a reversible hypometabolism mediated by α-ketoglutarate dehydrogenase deficiency, which is correlated with disease progression in the donating patients.

Sebastian Schmidt
Constantin Stautner
Wolfgang Wurst
ResearchOpen Access23 Nov 2023
Nature Communications

Volume: 14, P: 1-24
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’

High resolution characterisation of the virus specific T cell response to SARS CoV2 provides further understanding to the immune response to the infection. Here the authors apply a reverse phenotyping approach to interrogate the SARS-CoV-2 T cell compartment at single cell resolution.”

David S. Fischer
Meshal Ansari
Kilian Schober
ResearchOpen Access26 Jul 2021
Nature Communications

Volume: 12, P: 1-14
Optimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows

This study presents a comprehensive evaluation of Xenium In Situ datasets and provides recommendations on analysis workflows.

Sergio Marco Salas
Louis B. Kuemmerle
Mats Nilsson
ResearchOpen Access13 Mar 2025
Nature Methods

Volume: 22, P: 813-823
The proteome landscape of the kingdoms of life

An advanced proteomics workflow is used to identify 340,000 proteins from 100 taxonomically diverse species, providing a comparative view of proteomes across the evolutionary range.

Johannes B. Müller
Philipp E. Geyer
Matthias Mann
Research17 Jun 2020
Nature

Volume: 582, P: 592-596
The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology

Unbiased screening for insect gene function has been largely restricted to Drosophila. Here, Schmitt-Engel et al. perform an unbiased large-scale RNAi screen in the red flour beetle Tribolium castaneumto identify putative gene functions.

Christian Schmitt-Engel
Dorothea Schultheis
Gregor Bucher
ResearchOpen Access28 Jul 2015
Nature Communications

Volume: 6, P: 1-10
Quasi-experimental evaluation of a nationwide diabetes prevention programme

Analysis of the largest behaviour change programme for prediabetes globally provides causal evidence that lifestyle advice and counselling implemented at scale can improve key cardiovascular risk factors.

Julia M. Lemp
Christian Bommer
Pascal Geldsetzer
Research15 Nov 2023
Nature

Volume: 624, P: 138-144
Biodiversity offsets, their effectiveness and their role in a nature positive future

Biodiversity offsets, applied as part of the mitigation hierarchy, aim to ensure that ‘no net loss’ of biodiversity occurs as a result of human development projects and activities. This Review explores offsetting approaches, their effectiveness in comparison with other conservation mechanisms, and the future of offsetting in the context of ‘nature positive’ goals.

Martine Maron
Amrei von Hase
Sophus O. S. E. zu Ermgassen
Reviews28 Feb 2025
Nature Reviews Biodiversity

Volume: 1, P: 183-196
Associations between cardiac adipose tissue and abdominal visceral fat and muscle based on computed tomography area and density

Babak Salam
Sebastian Nowak
Julian A. Luetkens
ResearchOpen Access20 Jun 2025
Scientific Reports

Volume: 15, P: 1-9
Opportunistic CT-derived analysis of fat and muscle tissue composition predicts mortality in patients with cardiogenic shock

Babak Salam
Muntadher Al Zaidi
Julian A. Luetkens
ResearchOpen Access15 Dec 2023
Scientific Reports

Volume: 13, P: 1-9
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics

An integrated analysis of over 100 single-cell and single-nucleus transcriptomics studies illustrates severe acute respiratory syndrome coronavirus 2 viral entry gene coexpression patterns across different human tissues, and shows association of age, smoking status and sex with viral entry gene expression in respiratory cell populations.

Christoph Muus
Malte D. Luecken
Xiaohui Zhang
Research02 Mar 2021
Nature Medicine

Volume: 27, P: 546-559
Impact of timing and combination of different BNT162b2 and ChAdOx1-S COVID-19 basic and booster vaccinations on humoral immunogenicity and reactogenicity in adults

Simon Dedroogh
Sven Schmiedl
Michael Dedroogh
ResearchOpen Access03 Jun 2023
Scientific Reports

Volume: 13, P: 1-10
Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1

Lars Erichsen
Hans-Helge Seifert
Simeon Santourlidis
ResearchOpen Access02 Mar 2020
Scientific Reports

Volume: 10, P: 1-10

Search

Filter By:

Search

Quick links