The study uses GWAS for 40 circulating cytokines in meta-analyses of 74,783 individuals. With Mendelian randomization, key cytokines like G-CSF/CSF-3 and CXCL9/MIG are identified as potential causal mediators of asthma and Crohn’s disease, respectively.
- Marek J. Konieczny
- Murad Omarov
- Marios K. Georgakis