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Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities

The heterogeneity of IDH1/2 wild-type glioblastoma limits its prognosis and therapy. Here, the authors show a binary stratification, based on quantitative proteomic analysis of samples from patients with glioblastoma, with different prognosis and therapeutic vulnerabilities.

Sejin Oh
Jeonghun Yeom
Hyun Seok Kim
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-16
Sargassum horneri extract fermented by Lactiplantibacillus pentosus SH803 mediates adipocyte metabolism in 3T3-L1 preadipocytes by regulating oxidative damage and inflammation

Jae-Young Kim
Sejin Jang
Sae Hun Kim
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-12
3D keloid spheroid model: Development and application for personalized drug response prediction

3D keloid spheroid model combining fibroblasts and endothelial cells demonstrated enhanced viability and reflected patient heterogeneity, offering a promising platform for studying keloid pathogenesis and advancing precision medicine.

YoungHwan Choi
Hyung-Suk Jang
Jong Hee Lee
ResearchOpen Access08 Nov 2024
Communications Biology

Volume: 7, P: 1-12
High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases

Sejin Jang
Sung-Min Chun
Eunsil Yu
Research01 Nov 2013
Modern Pathology

Volume: 27, P: 731-739

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Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities

Sargassum horneri extract fermented by Lactiplantibacillus pentosus SH803 mediates adipocyte metabolism in 3T3-L1 preadipocytes by regulating oxidative damage and inflammation

3D keloid spheroid model: Development and application for personalized drug response prediction

High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases

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