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Showing 1–2 of 2 results
Advanced filters: Author: Sena Oten Clear advanced filters

  • In preclinical studies, the FDA approved TSP-1 antagonist gabapentin has been shown to disrupt neuronal-glioma interactions, slowing glioblastoma progression. Here, authors report a retrospective cohort study demonstrating a survival benefit associated with gabapentin in patients with newly diagnosed glioblastoma.

    • Joshua D. Bernstock
    • Mulki Mehari
    • Shawn L. Hervey-Jumper
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-6

  • Lis1 and Nde1/Ndel1 mediate the initiation of dynein-driven transport, but the mechanism remains unclear. Here, the authors reveal that Nde1 recruits Lis1 to autoinhibited dynein and promotes Lis1-mediated assembly of active dynein transport machinery.

    • Yuanchang Zhao
    • Sena Oten
    • Ahmet Yildiz
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14