The Prdm16 transcription factor is expressed preferentially in stem cells of the nervous- and the haematopoietic-system and is required for their maintenance. Prdm16 is shown to regulate reactive oxygen species (ROS) levels in the nervous system through an effect on the hepatocyte growth Factor (HGF) promoter.
- Sergei Chuikov
- Boaz P. Levi
- Sean J. Morrison