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Showing 1–2 of 2 results
Advanced filters: Author: Shamci Monajembashi Clear advanced filters

  • Cilia, tiny outgrowths of cells, are essential for life. Here, the author’s describe the scaffold protein TRIP6, which promotes the assembly of ciliary proteins required for ciliogenesis, and show that its absence results in hydrocephalus.

    • Shalmali Shukla
    • Ronny Haenold
    • Peter Herrlich
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • Organismal ageing is driven by conserved biological processes. Here the authors build on a comparative RNA-seq analysis in three model organisms to demonstrate that the gene, bcat-1, which catalyses the degradation of branched-chain amino acids, regulates lifespan in worms.

    • Johannes Mansfeld
    • Nadine Urban
    • Michael Ristow
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-12