Nature Search

Multidimensional tumor-blood profiling uncovers systemic lymphocyte-monocyte imbalance in pituitary neuroendocrine tumors

Yuting Dai
Shaojian Lin
Zhe Bao Wu
ResearchOpen Access18 Nov 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-17
Targeting parvalbumin promotes M2 macrophage polarization and energy expenditure in mice

Exercise increases energy expenditure and suppresses obesity, but the effector mechanisms are not still unclear. Here the authors profile serum proteomics in exercised mice to find reduced parvalbumin levels that correlate with increased M2 macrophage and suppressed diet-induced obesity to hint parvalbumin as a potential therapy target against obesity.

Shaojian Lin
Anke Zhang
Bing Luan
ResearchOpen Access08 Jun 2022
Nature Communications

Volume: 13, P: 1-15
Molecular epidemiology and population immunity of SARS-CoV-2 in Guangdong (2022–2023) following a pivotal shift in the pandemic

Release of the zero-COVID policy in China in late 2022 led to two large Omicron-driven waves of infection in 2023. Here, the authors analyze virus genomes and serology data from before and after the two waves and describe changes in virus lineage distribution and age-specific antibody responses.

Zhencui Li
Pei Hu
Jing Lu
ResearchOpen Access15 Aug 2024
Nature Communications

Volume: 15, P: 1-12
Sexual dimorphism in pituitary neuroendocrine tumours

Pituitary neuroendocrine tumours (PitNETs) exhibit notable sex-related differences, particularly in prolactinomas and corticotroph tumours. Findings from the past 5 years in other cancers suggest that interactions between sex hormones and the immune system, as well as epigenetic modifications specific to sex chromosomes, could influence sex differences in tumour development.

Shaojian Lin
Jun Li
Zhe Bao Wu
Comments & Opinion25 Feb 2025
Nature Reviews Endocrinology

Volume: 21, P: 263-264
High-spatiotemporal-resolution mapping of global urban change from 1985 to 2015

The world keeps urbanizing. This study finds that since 1985 global urban lands have expanded four times faster than previously recognized and faster than population is growing.

Xiaoping Liu
Yinghuai Huang
Zhenzhong Zeng
Research04 May 2020
Nature Sustainability

Volume: 3, P: 564-570
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition

Yue Zhu
Xinzhi Peng
Miaoyun Long
ResearchOpen Access18 Apr 2022
Cell Death & Disease

Volume: 13, P: 1-11

Quick links

Search

Filter By:

Multidimensional tumor-blood profiling uncovers systemic lymphocyte-monocyte imbalance in pituitary neuroendocrine tumors

Targeting parvalbumin promotes M2 macrophage polarization and energy expenditure in mice

Molecular epidemiology and population immunity of SARS-CoV-2 in Guangdong (2022–2023) following a pivotal shift in the pandemic

Sexual dimorphism in pituitary neuroendocrine tumours

High-spatiotemporal-resolution mapping of global urban change from 1985 to 2015

METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition

Search

Quick links