The structure of the N-terminal actin binding domain of human f imbrin offers the first view of an F-actin crosslinking protein and is representative of the conserved actin binding domain found in the largest family of crosslinking proteins. This domain is composed of two calponin homology domains and allows for the mapping of residues implicated in F-actin binding.
- Sharon C. Goldsmith
- Navin Pokala
- Steven C. Almo