Dmitry Gordenin, Gad Getz and colleagues report an analysis of mutation patterns in cancer genomes and find evidence of mutagenesis induced by APOBEC cytidine deaminase enzymes. They find an APOBEC mutagenesis pattern in bladder, cervical, breast, head and neck, and lung cancers, representing 68% of all mutations in some samples.
- Steven A Roberts
- Michael S Lawrence
- Dmitry A Gordenin
