Maria Karayiorgou, Joseph Gogos and colleagues sequenced the exomes of 53 sporadic schizophrenia cases and their parents as well as 22 unaffected control trios. They identified a large excess of non-synonymous de novo mutations in cases, supporting a role for de novo mutations in the etiology of this disease.
- Bin Xu
- J Louw Roos
- Maria Karayiorgou
