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Showing 1–2 of 2 results
Advanced filters: Author: Shen-Huan Liang Clear advanced filters

  • The fungus Candida albicans is ubiquitous and usually harmless in the human gut, but can also cause systemic infection. Here, Kakade et al. show that fungal secretion of an immunomodulatory toxin, candidalysin, activates a host IL-17-DUOX2 axis that regulates C. albicans colonization of the intestine.

    • Pallavi Kakade
    • Juan F. Burgueno
    • Richard J. Bennett
    ResearchOpen Access
    Nature Communications
    P: 1-15

  • Both the yeast and hyphal forms of Candida albicans enable colonization of the mammalian gut, with hyphal cells secreting the toxin candidalysin to inihibit bacteria and support fungal commensalism.

    • Shen-Huan Liang
    • Shabnam Sircaik
    • Richard J. Bennett
    Research
    Nature
    Volume: 627, P: 620-627