Nature Search

Bioinspired ruthenium-manganese-oxygen complex for biocatalytic and radiosensitization therapies to eradicate primary and metastatic tumors

Radiosensitising agents can enhance radiotherapy and improve outcomes. Here, the authors report on the design of bioinspired Radiosensitising and biocatalytic nanoparticles to increase radiation tiggered cell death and immunogenic response to combat both primary and metastatic tumours.

Ruidan Li
Ting Wang
Xingchen Peng
ResearchOpen Access16 Aug 2025
Nature Communications

Volume: 16, P: 1-18
Optical nonlinearities in excess of 500 through sublattice reconstruction

A strategy for engineering photon-avalanche nanoparticles is proposed such that they exhibit an unprecedentedly strong nonlinear optical response and their emissions scale by more than 500th power of the pump intensity.

Jiaye Chen
Chang Liu
Xiaogang Liu
Research18 Jun 2025
Nature

Volume: 643, P: 669-674
Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion

Chemo-resistance and immune evasion are major challenges in osteosarcoma treatment. Here the authors show that doxorubicin promotes IL-18 secretion by tumor associated macrophages inducing LAT2-dependent CD47 upregulation in osteosarcoma cells, suggesting LAT2 inhibition as a therapeutic option in combination with doxorubicin.

Zenan Wang
Binghao Li
Zhaoming Ye
ResearchOpen Access23 Oct 2022
Nature Communications

Volume: 13, P: 1-19
Deep learning modeling m⁶A deposition reveals the importance of downstream cis-element sequences

The site specificity of m6A mRNA modification is a fundamental RNA biology question. Here, Luo et al., develop the iM6A, a deep learning method to model this process, showing that its site-specificity is determined by the primary nucleotide sequence.

Zhiyuan Luo
Jiacheng Zhang
Shengdong Ke
ResearchOpen Access17 May 2022
Nature Communications

Volume: 13, P: 1-16
Exon-intron boundary inhibits m⁶A deposition, enabling m⁶A distribution hallmark, longer mRNA half-life and flexible protein coding

m⁶A mRNA modification is not typically found near splice junctions in mRNAs. Here the authors show exon-intron boundary inhibits m6A deposition at ~100 nt region nearby splice site, enabling m⁶A distribution hallmark, more stable mRNA and flexible protein coding.

Zhiyuan Luo
Qilian Ma
Shengdong Ke
ResearchOpen Access13 Jul 2023
Nature Communications

Volume: 14, P: 1-17
Efficient photocatalytic production of hydrogen peroxide using dispersible and photoactive porous polymers

Current industrial production of hydrogen peroxide suffers from hefty energy penalties and toxic byproducts. Here, the authors report efficient photocatalytic production of hydrogen peroxide by protonation-induced dispersible porous polymers with good charge-carrier transport properties.

Shengdong Wang
Zhipeng Xie
Cheng Gu
ResearchOpen Access28 Oct 2023
Nature Communications

Volume: 14, P: 1-7
Large-area patterning of full-color quantum dot arrays beyond 1000 pixels per inch by selective electrophoretic deposition

Colloidal quantum dots are promising for next-generation displays, yet the technology to realise high-resolution and uniform patterning is still scarce. Here, the authors report full-colour QD large area patterning by combining photolithography and selective electrophoretic deposition technique.

Jinyang Zhao
Lixuan Chen
Xiao Wei Sun
ResearchOpen Access29 Jul 2021
Nature Communications

Volume: 12, P: 1-8
Flexible high energy density zinc-ion batteries enabled by binder-free MnO₂/reduced graphene oxide electrode

Yuan Huang
Jiuwei Liu
Hang Zhou
ResearchOpen Access30 Jul 2018
npj Flexible Electronics

Volume: 2, P: 1-6
Analyzing vehicle path optimization using an improved genetic algorithm in the presence of stochastic perturbation matter

Shengdong Mu
Boyu Liu
Chen Xiaojie
ResearchOpen Access30 Oct 2024
Scientific Reports

Volume: 14, P: 1-16
Longitudinal change of serum AIM2 levels after aneurysmal subarachnoid hemorrhage and its prognostic significance: a two-center prospective cohort study

Ziyin Chen
Shengdong Zou
Dingbo Yang
ResearchOpen Access07 May 2024
Scientific Reports

Volume: 14, P: 1-21
An eye-movement database of bilingual language control for Chinese-English bilinguals

Tao Wang
Yue Wang
Yiming Yang
ResearchOpen Access25 Feb 2025
Scientific Data

Volume: 12, P: 1-7
Trait self-consciousness predicts amygdala activation and its functional brain connectivity during emotional suppression: an fMRI analysis

Shengdong Chen
Changming Chen
Jiajin Yuan
ResearchOpen Access08 Mar 2017
Scientific Reports

Volume: 7, P: 1-11
The modified theoretical model for debris flows predication with multiple rainfall characteristic parameters

Shengdong Cai
Zizhao Zhang
Yang Hu
ResearchOpen Access11 Apr 2025
Scientific Reports

Volume: 15, P: 1-15
Impaired 2′,3′-cyclic phosphate tRNA repair causes thermo-sensitive genic male sterility in rice

Bin Yan
Chunyan Liu
Xiaofeng Cao
Research09 Sept 2024
Cell Research

Volume: 34, P: 763-775
Knockdown of FOXA2 enhances the osteogenic differentiation of bone marrow-derived mesenchymal stem cells partly via activation of the ERK signalling pathway

Chenyi Ye
Mo Chen
Wei Zhang
ResearchOpen Access06 Aug 2018
Cell Death & Disease

Volume: 9, P: 1-13
Identification and characterization of human uracil phosphoribosyltransferase (UPRTase)

Jixi Li
Shengdong Huang
Yumin Mao
Research24 Mar 2007
Journal of Human Genetics

Volume: 52, P: 415-422
MED15 is upregulated by HIF-2α and promotes proliferation and metastasis in clear cell renal cell carcinoma via activation of SREBP-dependent fatty acid synthesis

Xiaoliang Hua
Shengdong Ge
Chaozhao Liang
ResearchOpen Access22 Apr 2024
Cell Death Discovery

Volume: 10, P: 1-16
Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway

Wei Zhang
Deting Xue
Zhijun Pan
ResearchOpen Access09 Jun 2016
Scientific Reports

Volume: 6, P: 1-11

Search

Bioinspired ruthenium-manganese-oxygen complex for biocatalytic and radiosensitization therapies to eradicate primary and metastatic tumors

Optical nonlinearities in excess of 500 through sublattice reconstruction

Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion

Deep learning modeling m⁶A deposition reveals the importance of downstream cis-element sequences

Exon-intron boundary inhibits m⁶A deposition, enabling m⁶A distribution hallmark, longer mRNA half-life and flexible protein coding

Efficient photocatalytic production of hydrogen peroxide using dispersible and photoactive porous polymers

Large-area patterning of full-color quantum dot arrays beyond 1000 pixels per inch by selective electrophoretic deposition

Flexible high energy density zinc-ion batteries enabled by binder-free MnO₂/reduced graphene oxide electrode

Analyzing vehicle path optimization using an improved genetic algorithm in the presence of stochastic perturbation matter

Longitudinal change of serum AIM2 levels after aneurysmal subarachnoid hemorrhage and its prognostic significance: a two-center prospective cohort study

An eye-movement database of bilingual language control for Chinese-English bilinguals

Trait self-consciousness predicts amygdala activation and its functional brain connectivity during emotional suppression: an fMRI analysis

The modified theoretical model for debris flows predication with multiple rainfall characteristic parameters

Impaired 2′,3′-cyclic phosphate tRNA repair causes thermo-sensitive genic male sterility in rice

Knockdown of FOXA2 enhances the osteogenic differentiation of bone marrow-derived mesenchymal stem cells partly via activation of the ERK signalling pathway

Identification and characterization of human uracil phosphoribosyltransferase (UPRTase)

MED15 is upregulated by HIF-2α and promotes proliferation and metastasis in clear cell renal cell carcinoma via activation of SREBP-dependent fatty acid synthesis

Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway

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