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Showing 1–2 of 2 results
Advanced filters: Author: Shiaulou Yuan Clear advanced filters

  • The O-glycosylation enzyme Galnt11 has an important role in heterotaxy, a disorder of left–right body patterning or laterality: Galnt11 modulates Notch signalling which alters cilia types at the embryonic left–right organizer, therefore determining laterality.

    • Marko T. Boskovski
    • Shiaulou Yuan
    • Mustafa K. Khokha
    Research
    Nature
    Volume: 504, P: 456-459

  • Cilia are now known to have broad roles in cardiac development and disease. In this Review, Yuan and colleagues discuss the latest findings that link cilia function and biogenesis to congenital heart disease and describe the role of cilia in the development of cardiac left–right asymmetry, haemodynamic mechanosensation, valvulogenesis and myocardial regeneration.

    • Lydia Djenoune
    • Kathryn Berg
    • Shiaulou Yuan
    Reviews
    Nature Reviews Cardiology
    Volume: 19, P: 211-227