Fujisawa and colleagues report that during a working memory task, firing patterns in ensembles of rat medial prefrontal cortex neurons reflect behavioral outcomes on coarser time scales and short-term synaptic plasticity on finer time scales. These results suggest that short-term plasticity plays a role in the neural computations guiding behavior.
- Shigeyoshi Fujisawa
- Asohan Amarasingham
- György Buzsáki