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Gene Therapy (3)
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Showing 1–7 of 7 results

Advanced filters: Author: Shih-Ching Lo Clear advanced filters

Aβ_1–42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β

Amyloid-β is known to inhibit hippocampal long-term potentiation (LTP), but the underlying molecular mechanisms are only partially understood. In this capacity, Jo and colleagues report the involvement of a signaling pathway comprised of caspase-3, Akt1 and glycogen synthase kinase-3β.

Jihoon Jo
Daniel J Whitcomb
Kwangwook Cho
Research27 Mar 2011
Nature Neuroscience

Volume: 14, P: 545-547
Characterization of Social Behaviors in caspase-3 deficient mice

Shih-Ching Lo
Kimberly Scearce-Levie
Morgan Sheng
ResearchOpen Access19 Jan 2016
Scientific Reports

Volume: 6, P: 1-9
Engineered microRNA scaffolds for potent gene silencing in vivo

Giuseppe Militello
Alyssa Greig
Prem K. Premsrirut
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model

Yi A. Chen
Mark W. Kankel
Shih-Ching Lo
Research01 Dec 2022
Gene Therapy

Volume: 30, P: 443-454
Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice

Sam Hana
Michael Peterson
Shih-Ching Lo
ResearchOpen Access08 Feb 2021
Gene Therapy

Volume: 28, P: 646-658
Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice

Tess Torregrosa
Sydney Lehman
Shih-Ching Lo
ResearchOpen Access22 Feb 2021
Gene Therapy

Volume: 28, P: 456-468
Nutritional support for successful weaning in patients undergoing prolonged mechanical ventilation

Shih-Ching Lo
Kevin Sheng-Kai Ma
Shun-Fa Yang
ResearchOpen Access14 Jul 2022
Scientific Reports

Volume: 12, P: 1-9