pH- and thermoresponsive polymer bearing pendant tertiary amino groups was grafted onto the surface of Resovist (PDMA@Rv). At pH 5.4, the grafted-polymer became hydrophilic, and the size of PDMA@Rv remained constant, irrespective of temperature. PDMA@Rv formed aggregates and showed lower critical solution temperature behavior above pH 7. PDMA@Rv contained a larger number of core particles of iron oxide than Resovist, which reduced the initial magnetic susceptibility due to the interaction of the core magnetic particles inside PDMA@Rv.
- Shinichiro Kano
- Kengo Takagi
- Shin-ichi Yusa
