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Showing 1–1 of 1 results
Advanced filters: Author: Shingo Obika Clear advanced filters

  • Daisuke Oikawa et al. provide structural insights into how small-molecule inhibitors of LUBAC ubiquitin ligase, HOIPINs, bind to LUBAC. They find that HOIPINs trigger apoptosis in lymphoma cells and alleviate psoriasis in mice, suggesting the potential therapeutic utility of HOIPINs.

    • Daisuke Oikawa
    • Yusuke Sato
    • Fuminori Tokunaga
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-17