Acute-on-chronic liver failure (ACLF) is a distinct clinical entity with a serious risk of death. However, much debate surrounds the pathogenesis and definitions of this disease. Sarin and Choudhury describe the differences and similarities between Eastern and Western definitions of ACLF and present a common approach to manage these patients for better clinical outcomes.
- Shiv K. Sarin
- Ashok Choudhury
