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Advanced filters: Author: Shun Yaginuma Clear advanced filters

  • GPR34 is a GPCR which has an immunomodulatory role and recognizes lysophosphatidylserine (LysoPS) as a putative endogenous ligand. Here, authors report two cryo-EM structures of human GPR34-Gi complex with one of two ligands bound: either the LysoPS analogue S3E-LysoPS, or its derivative M1.

    • Tamaki Izume
    • Ryo Kawahara
    • Osamu Nureki
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15