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Showing 1–2 of 2 results
Advanced filters: Author: Shunta Taminishi Clear advanced filters

  • In this study, the authors isolated SARS-CoV-2 receptor binding site monoclonal antibodies resistant to Omicron mutations. An amino acid in the receptor binding domain, tyrosine-489, is a virus-vulnerable site and a common footprint of broadly neutralizing antibodies.

    • Saya Moriyama
    • Yuki Anraku
    • Yoshimasa Takahashi
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Nonalcoholic steatohepatitis (NASH) starts with lipid droplet accumulation in the liver that eventually causes inflammation and fibrosis. Here, authors use lipophagy activators to limit the accumulation of lipids in the liver and show that this can prevent disease progression in a mouse model of nonalcoholic steatohepatitis.

    • Yoshito Minami
    • Atsushi Hoshino
    • Satoaki Matoba
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15