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Showing 1–2 of 2 results
Advanced filters: Author: Sigurd Wagner Clear advanced filters

  • Pflügler, Svinka et al. identify a subset of Paneth cells in mouse intestinal crypts and tumors, which express the immune checkpoint molecule Ido1 in a Stat1-dependent manner and promote tumor growth. Gene expression data from human colorectal cancer (CRC) suggest that a similar population is present in human cancer and opens the door for further studies of immune escape mechanisms in CRC.

    • Sandra Pflügler
    • Jasmin Svinka
    • Robert Eferl
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-14