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Advanced filters: Author: Silke Frahm Clear advanced filters

Nonlinear DNA methylation trajectories in aging male mice

DNA methylation is an age biomarker, but nonlinear aspects of its age-related dynamics are not well characterized. Here, the authors identify loci that undergo sudden methylation changes at specific life stages in the aging colon of male mice.

Maja Olecka
Alena van Bömmel
Steve Hoffmann
ResearchOpen Access09 Apr 2024
Nature Communications

Volume: 15, P: 1-15
Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids

George A Mashour
Stephanie N Drissel
Andreas Kurtz
Research14 Feb 2005
Oncogene

Volume: 24, P: 2367-2374
c-Jun inhibition mitigates chemotherapy-induced neurotoxicity in iPSC-derived sensory neurons

Lois Hew
Smilla K. Maierhof
Christian Schinke
ResearchOpen Access13 Nov 2025
Cell Death Discovery

Volume: 11, P: 1-12
Silencing neurotransmission with membrane-tethered toxins

The use of membrane-tethered toxins to selectively block ion channel function in vivo is demonstrated. The approach is applied to blockade of voltage-gated calcium channels for inhibition of neurotransmission in the mouse.

Sebastian Auer
Annika S Stürzebecher
Inés Ibañez-Tallon
Research07 Feb 2010
Nature Methods

Volume: 7, P: 229-236
Social enrichment by separated pair housing of male C57BL/6JRj mice

Katharina Hohlbaum
Silke Frahm
Kristina Ullmann
ResearchOpen Access07 Jul 2020
Scientific Reports

Volume: 10, P: 1-15