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Showing 1–3 of 3 results
Advanced filters: Author: Simona P. Pfister Clear advanced filters
  • Virulent pathogens generally induce a stronger mucosal immunity than avirulent strains, but whether the associated inflammation is necessary for this is unclear. Here, using auxotrophic Salmonella enterica, the authors show that virulence factor function determines induction of protective IgA.

    • Simona P. Pfister
    • Olivier P. Schären
    • Siegfried Hapfelmeier
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-18
  • Medulloblastoma is the most common brain tumour in children; using whole-genome sequencing of tumour samples the authors show that the clinically challenging Group 3 and 4 tumours can be tetraploid, and reveal the expression of the first medulloblastoma fusion genes identified.

    • David T. W. Jones
    • Natalie Jäger
    • Peter Lichter
    ResearchOpen Access
    Nature
    Volume: 488, P: 100-105