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Showing 1–2 of 2 results
Advanced filters: Author: Sin Fun Sia Clear advanced filters

  • The pathogenicity and transmissibility of SARS-CoV-2 in golden (Syrian) hamsters resemble features of COVID-19 in human patients, suggesting that these hamsters could be used to model this disease.

    • Sin Fun Sia
    • Li-Meng Yan
    • Hui-Ling Yen
    Research
    Nature
    Volume: 583, P: 834-838

  • The inherent inaccuracy of viral RNA polymerases promotes viral evolution, but the importance of viral genetic diversity during infection is unclear. Here, Cheung et al.show that influenza strains with enhanced polymerase fidelity and low mutational frequency display reduced pathogenicity in mice.

    • Peter P. H. Cheung
    • Simon J. Watson
    • Hui-Ling Yen
    Research
    Nature Communications
    Volume: 5, P: 1-13