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Showing 1–2 of 2 results
Advanced filters: Author: Sindhuja Gowrisankaran Clear advanced filters
  • Time-resolved electron microscopy reveals that intersectin-1 and endophilin A1 condensates hold replacement synaptic vesicles close to release sites. Without this, replacement vesicles are unavailable for immediate use, causing synaptic depression in response to stimulation trains.

    • Tyler H. Ogunmowo
    • Christian Hoffmann
    • Shigeki Watanabe
    ResearchOpen Access
    Nature Neuroscience
    Volume: 28, P: 1649-1662
  • Endophilins-A are conserved membrane-associated proteins required for endocytosis. Here, the authors report that endophilins-A also promote exocytosis of neurosecretory vesicles by coordinating priming and fusion through intersectin-1, independently of their roles in different types of endocytosis.

    • Sindhuja Gowrisankaran
    • Sébastien Houy
    • Ira Milosevic
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-18