RNA modifications have emerged as important regulators of RNA function. In this study, Peng, Chen, Wei and Guo et al. show that the 18S rRNA N6-methyladenosine methyltransferase complex METTL5–TRMT112 regulates hepatic lipid metabolism and contributes to hepatocellular carcinoma.
- Hao Peng
- Binbin Chen
- Shuibin Lin