Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Sonal Deshpande Clear advanced filters

  • Formation of biomolecular condensates composed of proteins and RNA facilitates the regulation of gene expression by modulating translation or facilitating RNA processing. Now, synthetic ribonucleoprotein granules created with engineered intrinsically disordered proteins selectively sequester mRNA and enhance protein translation in cells. These highly liquid-like condensates exchange biomolecules across the cell and facilitate target mRNA and ribosome partitioning.

    • Daniel Mark Shapiro
    • Sonal Deshpande
    • Ashutosh Chilkoti
    Research
    Nature Chemistry
    Volume: 17, P: 448-456

  • Insoluble protein expression continues to be a bottleneck for biotechnology. Here, Chilkoti and colleagues report a method for generating and identifying hypersoluble intrinsically disordered protein fusion tags to improve soluble protein expression and rescue protein function.

    • Nicholas C. Tang
    • Jonathan C. Su
    • Ashutosh Chilkoti
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15