Near-infrared-II carbon dots offer exceptional deep-tissue penetration for biomedical imaging, but challenges remain in their synthesis and photoluminescence mechanisms. In this work, the authors designed and synthesized a series of carbon dots (CDs-1 to CDs-3) through extension of aniline-based frameworks, achieving tunable emission extending into the NIR-II region, and applied these CDs in deeptissue NIR-II imaging of the hepatobiliary system.
- Lijuan Yang
- Man Li
- Gang Liu