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Advanced filters: Author: Sonja LaBianca Clear advanced filters

Changes in polygenic burden for psychiatric disorders across two decades of birth cohorts

Lousdal et al. investigate the changes in polygenic scores for schizophrenia, depression, autism and attention deficit hyperactivity disorder using data from a Danish population-based case–cohort study that includes individuals born between 1981 and 2008.

Mette Lise Lousdal
Sonja LaBianca
Oleguer Plana-Ripoll
Research08 Sept 2025
Nature Mental Health

Volume: 3, P: 1037-1045
Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder

Genome-wide analyses yield insights into the polygenic effects contributing to clinical heterogeneity in attention deficit hyperactivity disorder, advancing understanding of its genetic etiology and serving as a model for future studies in other complex disorders.

Sonja LaBianca
Isabell Brikell
Andrew J. Schork
Research30 Nov 2023
Nature Genetics

Volume: 56, P: 234-244

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Changes in polygenic burden for psychiatric disorders across two decades of birth cohorts

Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder

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