The tumor suppressor p53 activates the transcription of a number of genes under conditions of genotoxic stress. Some of these regulated promoters show p53 occupancy even under normal conditions. Now calcineurin-binding protein 1 (Cabin1) is shown to keep p53 inactive in these promoters.
- Hyonchol Jang
- Soo-Youn Choi
- Hong-Duk Youn
