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Showing 1–4 of 4 results
Advanced filters: Author: Spartak Zikrin Clear advanced filters

  • What makes a transcription factor (TF) binding site “strong”: slow TF dissociation, or fast TF association? Kandavalli et al found that stronger sites had both slower dissociation and faster association compared to weaker sites in vivo.

    • Vinodh Kandavalli
    • Spartak Zikrin
    • Daniel Jones
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-9

  • DuMPLING (dynamic μ-fluidic microscopy phenotyping of a library before in situ genotyping) enables screening of dynamic phenotypes in strain libraries and was used here to study genes that coordinate replication and cell division in Escherichia coli.

    • Daniel Camsund
    • Michael J. Lawson
    • Johan Elf
    Research
    Nature Methods
    Volume: 17, P: 86-92

  • Optical pooled screening of libraries with genomic barcodes has not previously been achieved in bacteria. Here we describe such a method in E. coli and apply it to measure the intracellular maturation time of 84 red fluorescent proteins.

    • Ruben R. G. Soares
    • Daniela A. García-Soriano
    • Johan Elf
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-9