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Showing 1–7 of 7 results
Advanced filters: Author: Stéphane Noselli Clear advanced filters

  • Left-right (LR) axis specification is essential for embryonic patterning but a unifying mechanism across organisms has not been identified. Here, the authors show that Myosin1D, known to regulate Drosophila LR asymmetry, controls zebrafish LR Organizer function, and is therefore a conserved regulator of animal laterality.

    • Thomas Juan
    • Charles Géminard
    • Maximilian Fürthauer
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12

  • FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

    • Sven Dorkenwald
    • Arie Matsliah
    • Meet Zandawala
    ResearchOpen Access
    Nature
    Volume: 634, P: 124-138

  • The combined use of laser ablation and live imaging in Drosophila melanogaster embryos provides new ways to visualize the dynamics of wound healing. Analysis of lesions made in living embryos mutant for small GTPases reveal distinct and unexpected roles for actin cables and protrusions in wound repair. Hole closure is definitely more complex than simply pulling a string.

    • Stéphane Noselli
    News & Views
    Nature Cell Biology
    Volume: 4, P: E251-E253

  • Active regulation of chirality, or handedness, is crucial for life. Here, the authors describe assays to characterise proteome chirality in vivo and show that errors degrade enzyme activity triggering tumour formation and reduced lifespan.

    • Agnes Banreti
    • Shayon Bhattacharya
    • Stéphane Noselli
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15