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Showing 1–2 of 2 results
Advanced filters: Author: Stefania Monteverde Clear advanced filters

  • Strategies aimed at promoting muscle regeneration to treat muscular dystrophy have met with limited success. Here the authors show instead that delaying muscle regeneration, by ablation of the transcription factor Nfix, ameliorates muscular dystrophy in mice.

    • Giuliana Rossi
    • Chiara Bonfanti
    • Graziella Messina
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • Mesoangioblasts are mesodermal stem cells with a therapeutic potential for treatment of muscular dystrophy due to their ability to differentiate into skeletal muscle. This study shows that the PW1/Peg3 protein is crucial for mesoangioblast myogenic and migratory potency and is a therapeutically relevant biomarker.

    • Chiara Bonfanti
    • Giuliana Rossi
    • Graziella Messina
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13